High serum CCL18 predicts a poor prognosis in patients with laryngeal squamous cell carcinoma

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Reduced miR-300 expression predicts poor prognosis in patients with laryngeal squamous cell carcinoma.

OBJECTIVE miR-300 has been demonstrated to play an important role in the progression of several tumors, but its role in tumorigenesis of laryngeal squamous cell carcinoma (LSCC) is still unclear. The purpose of this study was to explore miR-300 expression in LSCC patients and analyze its association with clinicopathological factors and prognosis. PATIENTS AND METHODS In the present study, we ...

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Cyclin D1 Expression in Patients with Laryngeal Squamous Cell Carcinoma

Background & Objective: Laryngeal squamous cell carcinoma (LSCC) is considered to be one of the most common cancers of the head and neck, accounting for roughly 90% of all malignant tumors of the larynx. To have a timely diagnosis for a better and practical therapy, molecular markers have to be investigated. The aim of this study was to determine the expression of Cyclin D1 (CD...

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Decreased 5-Hydroxymethylcytosine (5-hmC) predicts poor prognosis in early-stage laryngeal squamous cell carcinoma.

Accumulating evidences suggest that large-scale loss of 5-hydroxymethylcytosine (5-hmC) is an epigenetic hallmark in different cancers. However, the levels of 5-hmC in laryngeal squamous cell carcinoma (LSCC) and its prognostic value in this cancer remain largely unknown. Using dot-blot and quantitative RT-PCR assays, we investigate 5-hmC levels and expression of TET-1, -2 and -3 in LSCCs and e...

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High microRNA-23a expression in laryngeal squamous cell carcinoma is associated with poor patient prognosis

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ژورنال

عنوان ژورنال: Journal of Cancer

سال: 2019

ISSN: 1837-9664

DOI: 10.7150/jca.37515